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Study identifier: NCT05727163 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients

Condition: Colorectal Cancer Metastatic  ·  Sponsor: Sun Yat-sen University

PhasePhase 2
Planned participants194
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This prospective, randomized, controlled clinical study aims to evaluate the objective remission rate of FOLFOX hepatic artery infusion chemotherapy (HAI) in combination with systemic irinotecan with or without bevacizumab versus systemic intravenous FOLFOXIRI with or without bevacizumab in initially unresectable RAS-mutated colorectal cancer patients with liver metastases.

This description comes directly from the study's public registry record.

Talk to the study team

Li Yuhong  ·  020-87342487  ·  liyh@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05727163