Condition: Spinal Cord Injuries · Hypotension · Orthostatic Hypotension · Sponsor: Kessler Foundation
This project will investigate the effect of spinal cord transcutaneous stimulation on blood pressure in individuals with a chronic spinal cord injury who experience blood pressure instability, specifically, orthostatic hypotension (a drop in blood pressure when moving from lying flat on your back to an upright position). The main questions it aims to answer are: 1. What are the various spinal sites and stimulation parameters that normalize and stabilize blood pressure during an orthostatic provocation (70 degrees tilt)? 2. Does training, i.e., exposure to repeated stimulation sessions, have an effect on blood pressure stability? Participants will undergo orthostatic tests (lying on a table that starts out flat, then tilts upward up to 70 degrees), with and without stimulation, and changes in their blood pressure will be evaluated.
This description comes directly from the study's public registry record.
LeighAnn Martinez, BA · (973)324-3557 · lmartinez@kesslerfoundation.org
Einat Engel-Haber, MD · ehaber@kesslerfoundation.org
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| Kessler Foundation | West Orange, New Jersey, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05725499