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Study identifier: NCT05723588 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neuroimaging Correlates and Feasibility of Transcranial Magnetic Stimulation (TMS) to Improve Smoking Cessation Outcomes in Veterans With Comorbid PTSD

Condition: Tobacco Use Disorder  ·  Sponsor: VA Office of Research and Development

PhasePhase 2
Planned participants50
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Tobacco use is the number one preventable cause of the death in the United States, and is high among US Veterans, and those who have experienced trauma are more likely to smoke. Despite the efficacy of current evidence-based treatments for smoking cessation, there is a critical need for alternative treatments. This project seeks to evaluate the feasibility and effectiveness of a smoking cessation treatment for Veterans with posttraumatic stress disorder (PTSD) who smoke. The treatment combines smoking cessation counseling, nicotine replacement therapy (e.g., nicotine gum), and repetitive transcranial magnetic stimulation (rTMS). rTMS is a noninvasive brain stimulation treatment that has been cleared by the Food and Drug Administration for smoking cessation in adults.

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan R Young, MD  ·  (919) 286-0411  ·  jonathan.young14@va.gov

Angela C Kirby, MS  ·  (919) 286-0411  ·  angela.kirby@va.gov

Always discuss trial participation with your own doctor first.

Locations (1)

Durham VA Medical Center, Durham, NCDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05723588