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Study identifier: NCT05722561 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

E-Cigarettes for Harm Reduction in Smokers With Opioid Use Disorder

Condition: Opioid Use Disorder · Cigarette Smoking  ·  Sponsor: NYU Langone Health

PhasePhase 2
Planned participants302
Who can joinAll sexes, 21 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this an open-label, randomized controlled trial study is to compare the effectiveness of electronic cigarettes (e-cigarettes/e-cigs) versus telehealth motivational counseling with combination nicotine replacement therapy (NRT) + telehealth counseling on combustible cigarettes smoking reduction among persons with opioid use disorder (OUD) in methadone and buprenorphine treatment programs (opioid use disorder treatment programs (OUDTP)). OUDTP patients are a population with exceptionally high combustible cigarettes smoking burden and yet limited success in achieving meaningful clinical outcomes in tobacco treatment. If effective, electronic cigarettes would provide an additional tool for tobacco harm reduction among this difficult-to-treat vulnerable population.

This description comes directly from the study's public registry record.

Talk to the study team

Omar El-Shahawy, MD, MPH, PhD  ·  646-501-3587  ·  Omar.ElShahawy@nyulangone.org

Mohsen Abbasi, MD, MPH  ·  646-501-3581  ·  Mohsen.Abbasikangevari@nyulangone.org

Always discuss trial participation with your own doctor first.

Locations (2)

NYU Langone HealthNew York, New York, United StatesRecruiting
Albert Einstein College of MedicineThe Bronx, New York, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05722561