Condition: Hepatocellular Carcinoma · Sponsor: Sun Yat-sen University
Immune checkpoint inhibitors (ICIs) plus antiangiogenic agents can achieve better efficacy than sorafenib in the treatment of hepatocellular carcinoma (HCC) within a certain period of time, but more than half of the patients are still insensitive to the treatment. There is no evidence-based basis for second-line treatment after the progression of the disease.In view of the effectiveness of Hepatic arterial infusion (HAIC) in the first-line treatment of HCC in the Chinese population, this study intends to launch a prospective intervention study to explore the efficacy and safety of HAIC treatment in patients with advanced HCC after the failure of ICIs and antiangiogenic agents combination therapy, and to provide high-level evidence for optimizing the second-line treatment of advanced HCC in the future.
This description comes directly from the study's public registry record.
Ming Zhao, M.D. & Ph.D. · +86-20-87343272 · zhaoming@sysucc.org.cn
Ning Lyu, M.D. · +86-20-87343272 · lvning@sysucc.org.cn
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| Department of Minimally Invasive and Interventional Radiology, Liver Cancer Study and Service Group, Sun Yat-sen University Cancer Center | Guangzhou, Guangdong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05718492