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Study identifier: NCT05717218 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Ultra-protective Ventilation Monitored by Electrical Impedance Tomography in Patients With Severe Acute Respiratory Distress Syndrome on Veno-venous ECMO

Condition: Severe ARDS  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

For ECMO supported patients with severe ARDS (acute respiratory distress syndrome), usual care include use of "ultraprotective" mechanical ventilation with tidal volume and pressure reductions that might ultimately enhance lung protection of patients with ARDS. Although very low tidal might also cause pulmonary derecruitment. The aim of this study is to monitor effects of very low tidal volume on regression of overdistension and derecruitment using electrical impedance tomography. Secondary aim is to describe the evolution of the optimal PEEP (Positive End Expiratory Pressure) during the decrease of the tidal volume

This description comes directly from the study's public registry record.

Talk to the study team

Matthieu Pr SCHMIDT  ·  01 42 16 29 37  ·  matthieu.schmidt@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Service de médecine intensive - réanimation Hopital Pitié SalpêtrièreParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05717218