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Study identifier: NCT05717166 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor.

Condition: Metastatic Tumor  ·  Sponsor: David Palma

PhasePhase 3
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a phase III multi-institutional randomized trial. Patients will be randomized in a 1:2 ratio between current standard of care treatment (Arm 1) vs. standard of care treatment + SABR (Arm 2) to sites of known disease. Patients will be stratified by two of the strongest prognostic factors, based on a large multi-institutional analysis3: histology (Group 1: hormone-sensitive prostate cancer, breast, or renal; Group 2: all others), and number of metastases (Group 1: 1-3; Group 2: 4-10).

This description comes directly from the study's public registry record.

Talk to the study team

David Palma, MD, PhD  ·  519-685-8650  ·  David.Palma@lhsc.on.ca

Always discuss trial participation with your own doctor first.

Locations (5)

BC Cancer - Centre for the NorthPrince George, British Columbia, CanadaNot Yet Recruiting
BC Cancer - VancouverVancouver, British Columbia, CanadaRecruiting
London Regional Cancer Program of the Lawson Health Research InstituteLondon, Ontario, CanadaRecruiting
Centre Hospitalier de l'Université de Montréal-CHUMMontreal, Quebec, CanadaRecruiting
Universitätsspital ZürichZurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05717166