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Study identifier: NCT05715931 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Perioperative Chemotherapy Plus Trastuzumab Plus Toripalimab in HER2 Positive Locally Advanced Gastric or Esophagogastric Junction Adenocarcinoma

Condition: Adenocarcinoma of the Stomach · Adenocarcinoma of Esophagogastric Junction · HER2-positive Gastric Cancer  ·  Sponsor: Yu jiren

PhasePhase 2
Planned participants30
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study is a prospective, single arm, multi-center phase II clinical trial designed to evaluate the efficacy and safety of perioperative chemotherapy with FLOT regimen and trastuzumab in combination with toripalimab in participants with resectable HER2 positive locally advanced gastric or esophagogastric junction adenocarcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Jiren Yu  ·  0086-0571-87237931  ·  yujr0909@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (8)

The First Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhou, Zhejiang, ChinaRecruiting
The Second Affiliated Hospital, College of Medicine, Zhejiang UniversityHangzhou, Zhejiang, ChinaNot Yet Recruiting
Huzhou Central HospitalHuzhou, Zhejiang, ChinaNot Yet Recruiting
Lishui Central HospitalLishui, Zhejiang, ChinaNot Yet Recruiting
Ningbo First HospitalNingbo, Zhejiang, ChinaNot Yet Recruiting
Ningbo Medical Center LiHuiLi HospitalNingbo, Zhejiang, ChinaNot Yet Recruiting
Ningbo Second HospitalNingbo, Zhejiang, ChinaNot Yet Recruiting
Taizhou HospitalTaizhou, Zhejiang, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05715931