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Study identifier: NCT05714774 Synced from ClinicalTrials.gov · July 28, 2026
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Evaluation of Different Methods of Ultrasound Image Analysis for Real-time Monitoring of HIFU Prostate Cancer Treatment

Condition: Prostatic Neoplasms  ·  Sponsor: Hospices Civils de Lyon

PhaseNA
Planned participants40
Who can joinMale, 50 Years to no upper limit
Healthy volunteersNo

About this study

The ELASTO-US study is a single center feasibility study to evaluate 3 methods of analyzing real-time ultrasound images acquired during High Intensity Focused Ultrasound (HIFU) treatment in patients with localized prostate cancer. Real-time ultrasound acquisitions will be programmed at specific times and recorded during HIFU treatment. At the end of the treatment, these recordings will be exported in an anonymized way and analyzed according to the 3 different methods. A multiparametric-MRI will be performed in addition to the usual practice within 5 days after the treatment in order to control the area necroticised by the treatment. The mp-MRI will be the reference method against which the results obtained by the 3 methods of ultrasound image analysis will be compared. Techniques capable of providing safe and robust information on the progress of HIFU-generated necrosis would greatly limit the risks of overtreatment that can lead to side effects such as urinary incontinence as well as the risks of under treatment that can lead to cancer recurrence.

This description comes directly from the study's public registry record.

Talk to the study team

Sébastien Crouzet, Pr  ·  04 72 11 03 25  ·  Sebastien.crouzet@chu-lyon.fr

Marjolaine Beaudoin, Msc  ·  0472117494  ·  Marjolaine.beaudoin@chu-lyon.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Service d'Urologie et Chirurgie de la Transplantation - Hôpital Edouard Herriot - Hospices Civils de LyonLyon, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05714774