Condition: Heart Failure · Left Ventricular Systolic Dysfunction · Sponsor: Merck Sharp & Dohme LLC
This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period. The primary hypothesis is that vericiguat is superior to placebo in reducing NT-proBNP at Week 16 of the Base Period.
This description comes directly from the study's public registry record.
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| The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 0002) | Los Angeles, California, United States | Recruiting |
| Lucile Packard Children's Hospital ( Site 0040) | Palo Alto, California, United States | Recruiting |
| Loma Linda University Health System ( Site 0008) | San Bernardino, California, United States | Recruiting |
| Children's Hospital Colorado ( Site 0012) | Aurora, Colorado, United States | Recruiting |
| Children's National Medical Center ( Site 0020) | Washington D.C., District of Columbia, United States | Recruiting |
| Johns Hopkins All Children's Hospital ( Site 0029) | St. Petersburg, Florida, United States | Recruiting |
| Children's Healthcare of Atlanta - Arthur M. Blank Hospital ( Site 0001) | Atlanta, Georgia, United States | Recruiting |
| Boston Children's Hospital ( Site 0035) | Boston, Massachusetts, United States | Recruiting |
| C.S. Mott Children's Hospital ( Site 0033) | Ann Arbor, Michigan, United States | Recruiting |
| Washington University-Pediatric Cardiology/ St. Louis Children's Hospital ( Site 0006) | St Louis, Missouri, United States | Recruiting |
| Columbia University Medical Center-Pediatric Cardiology ( Site 0016) | New York, New York, United States | Recruiting |
| The Children's Hospital at Montefiore ( Site 0030) | The Bronx, New York, United States | Recruiting |
+ 95 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05714085