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Study identifier: NCT05711173 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clonal Hematopoiesis and NETs Formation in Venous Thrombosis (CLODETTE)

Condition: Venous Thromboses · Thromboembolic Disease · Neutrophil Extracellular Trap Formation  ·  Sponsor: University Hospital, Bordeaux

PhaseNA
Planned participants150
Who can joinAll sexes, 6 Years to 50 Years
Healthy volunteersNo

About this study

Thrombo-embolic venous diseases are represented by deep venous thrombosis and/or pulmonary embolism. In some patients with repeated thrombosis or occurrence of thrombosis in unusual sites, the etiological workup remains negative, which represents a problem for the management of the anticoagulant treatments. Recently, two factors have been identified as important in the physiopathology of hemostasis and coagulation: the presence of clonal hematopoiesis of indetermined potential (CHIP) and the formation of neutrophil extracellular traps (NETs). In this study, these two factors will be studied in patients with repeated venous thrombosis or thrombosis occurring in unusual site.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandre GUY  ·  0557656478  ·  alexandre.guy@chu-bordeaux.fr

Chloé JAMES  ·  0557891979  ·  chloe.james@chu-bordeaux.fr

Always discuss trial participation with your own doctor first.

Locations (7)

CHU de Bordeaux, Service de NeurologieBordeaux, FranceNot Yet Recruiting
CHU de Bordeaux, Service Gastro-EntérologieBordeaux, FranceNot Yet Recruiting
CHU de Bordeaux, Service Hématologie BiologiqueBordeaux, FranceRecruiting
CHU de Bordeaux, Service Médecine VasculaireBordeaux, FranceRecruiting
CHU de Bordeaux, Unité ambulatoire de Médecine VasculaireBordeaux, FranceRecruiting
CHU de Lille, Service Hémostase CliniqueLille, FranceNot Yet Recruiting
APHM - Hôpital de la Timone, Service HématologieMarseille, FranceNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT05711173