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Study identifier: NCT05705570 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies

Condition: Acute Lymphoblastic Leukemia, in Relapse · Acute Lymphoblastic Leukemia Refractory · B-cell Lymphoma Recurrent  ·  Sponsor: Nelson Hamerschlak

PhasePhase 1
Planned participants30
Who can joinAll sexes, 2 Years to 70 Years
Healthy volunteersNo

About this study

This is a phase l, single arm, prospective open, dose-escalation study in patients with relapsed or refractory CD19-positive B cell malignancies (ALL, NHL, CLL). The trial will include adult and pediatric patients. There will be three individual cohorts, defined by disease biology: pediatric ALL and aggressive pediatric NHL (Cohort 1), adult ALL (Cohort 2) and adult NHL/CLL (Cohort 3).

This description comes directly from the study's public registry record.

Talk to the study team

Nelson Hamerschlak, MD, PhH  ·  +551121517248  ·  hamer@einstein.br

Lucila N Kerbauy, MD, PhD  ·  +5511998667557  ·  lucila.kerbauy@einstein.br

Always discuss trial participation with your own doctor first.

Locations (1)

Hospital Israelita Albert EinsteinSão Paulo, São Paulo, BrazilRecruiting

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Source record: clinicaltrials.gov/study/NCT05705570