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Study identifier: NCT05705024 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

Condition: Corneal Ulcer  ·  Sponsor: University of Illinois at Chicago

PhasePhase 2
Planned participants38
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of allogeneic bone marrow-derived MSCs in patients with nonhealing epitheliopathy (IRB Protocol 2020-0334). In the present study, we want to study the efficacy of this treatment on chronic epitheliopathies.

This description comes directly from the study's public registry record.

Talk to the study team

Ali R Djalilian, MD  ·  312-996-8937  ·  adjalili@uic.edu

Charlotte E Joslin, OD, PhD  ·  312-996-5410  ·  charjosl@uic.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Department of Ophthalmology and Visual SciencesChicago, Illinois, United StatesRecruiting
University of Maryland at BaltimoreBaltimore, Maryland, United StatesRecruiting
Mass Eye and Ear InfirmaryBoston, Massachusetts, United StatesActive Not Recruiting
University of Pennsylvania, Scheie Eye InstitutePhiladelphia, Pennsylvania, United StatesActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT05705024