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Study identifier: NCT05703425 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of Sulfasalazine on CRH Levels in Pregnant Women

Condition: Preterm Birth  ·  Sponsor: Rutgers, The State University of New Jersey

PhasePhase 2
Planned participants50
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this randomized clinical trial is to assess sulfasalazine as a potential treatment to prevent recurrent preterm birth. The main questions it aims to answer are: * Does sulfasalazine down regulate corticotropin releasing hormone (CRH) levels in pregnant persons with a prior history of preterm birth? * Does sulfasalazine reduce the incidence of recurrent preterm birth in pregnant persons given drug vs. controls? Consenting participants will be randomized to receive sulfasalazine or to a control group and will undergo serial blood draws to assess plasma CRH levels.

This description comes directly from the study's public registry record.

Talk to the study team

Vanessa Martinez, MPH  ·  2017379179  ·  vm310@rwjms.rutgers.edu

Emily Rosenfeld, DO  ·  7324024960  ·  er720@rwjms.rutgers.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Rutgers Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05703425