Condition: Congenital Pulmonary Airway Malformation · Sponsor: Erasmus Medical Center
The goal of this clinical trial is to compare conservative wait-and-see management to elective surgical intervention, in asymptomatic Congenital Pulmonary Airway Malformation (CPAM) children. Children assigned to the intervention group will undergo surgical resection of the CPAM between 6 and 9 months of age. Children assigned to the control group will be monitored conservatively. The follow-up scheme will be uniform for both treatment groups and last for 5 years. The primary outcome is the difference in maximal endurance at five years of age between the surgical and conservative group. Secondary outcome measures are molecular genetic diagnostics, validated questionnaires - on parental anxiety, quality of life and health care consumption -, repeated imaging, and pulmonary morbidity during follow-up, as well as surgical complications and histopathology.
This description comes directly from the study's public registry record.
J Marco Schnater, MD, PhD · 0031 107036923 · j.schnater@erasmusmc.nl
Rene MH Wijnen, professor · 0031 107036923 · r.wijnen@erasmusmc.nl
Always discuss trial participation with your own doctor first.
| Radboud University Medical Centre | Nijmegen, Gelderlanf, Netherlands | Not Yet Recruiting |
| Erasmus MC Sophia Children's Hospital | Rotterdam, South Holland, Netherlands | Recruiting |
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05701514