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Study identifier: NCT05701358 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

Condition: Acute Myocardial Infarction · Coronary Artery Disease  ·  Sponsor: Population Health Research Institute

PhaseNA
Planned participants5100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

COMPLETE-2 is a prospective, multi-centre, randomized controlled trial comparing a strategy of physiology-guided complete revascularization to angiography-guided complete revascularization in patients with acute ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease (CAD) who have undergone successful culprit lesion Percutaneous Coronary Intervention (PCI). COMPLETE-2 OCT is a large scale, prospective, multi-centre, observational, imaging study of patients with STEMI or NSTEMI and multivessel CAD in a subset of eligible COMPLETE-2 patients.

This description comes directly from the study's public registry record.

Talk to the study team

COMPLETE-2 Project Office  ·  (905) 521-2100  ·  complete-2@phri.ca

Always discuss trial participation with your own doctor first.

Locations (113)

UCLALos Angeles, California, United StatesRecruiting
University of California, San FranciscoSan Francisco, California, United StatesRecruiting
Cardiovascular Research Institute of KansasWichita, Kansas, United StatesRecruiting
The Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesRecruiting
University of MichiganAnn Arbor, Michigan, United StatesRecruiting
Metropolitan Cardiology Consultants / Metropolitan Heart and Vascular Institute (MCC/MHVI)Coon Rapids, Minnesota, United StatesRecruiting
RWJ Barnabas HealthJersey City, New Jersey, United StatesRecruiting
Bassett Medical CenterCooperstown, New York, United StatesRecruiting
VA New York Harbor HealthCare SystemNew York, New York, United StatesRecruiting
NYU Grossman School of MedicineNew York, New York, United StatesRecruiting
Montefiore Medical CenterThe Bronx, New York, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting

+ 101 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05701358