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Study identifier: NCT05701306 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

APG-115 Alone or in Combination With APG-2575 in Children With Recurrent or Refractory Neuroblastoma or Solid Tumors

Condition: Neuroblastoma · Solid Tumor  ·  Sponsor: Ascentage Pharma Group Inc.

PhasePhase 1
Planned participants100
Who can joinAll sexes, 12 Years to 18 Years
Healthy volunteersNo

About this study

An open, non-randomized Phase I trial of dose-escalation and cohorts expansion to evaluate the safety, pharmacokinetic profile and initial efficacy of APG-115 alone or in combination with APG-2575 in the treatment of recurrent or refractory pediatric neuroblastoma or solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Yifan Zhai, MD,PHD  ·  +86-20-28068501  ·  Yzhai@ascentage.com

Yan Yu  ·  Yan.Yu@ascentage.com

Always discuss trial participation with your own doctor first.

Locations (3)

Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Tongji Hospital, Huazhong University of Science and Technology (HUST)Wuhan, Hubei, ChinaRecruiting
Tianjin Medical University Cancer Institute & HospitalTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05701306