Condition: Depression · ECT · Cognitive Change · Sponsor: University of New Mexico
A randomized controlled trial will compare hippocampal neuroplasticity, antidepressant, and cognitive outcomes between individualized amplitude and fixed 800 mA amplitude ECT in older depressed subjects (n = 25 per group, n = 50 total). Relative to fixed 800 mA ECT: H1: Individualized amplitude arm will have improved RUL antidepressant outcome (IDS-C30 response rates and reduced BT electrode placement switch at V2). H2: Individualized amplitude arm will have improved cognitive outcomes (DKEFS-Verbal Fluency
This description comes directly from the study's public registry record.
Chris Abbott, MD · 5052720406 · cabbott@salud.unm.edu
Megan Lloyd, MS · (505) 272-3507 · meglloyd@salud.unm.edu
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| University of New Mexico Health Science Center | Albuquerque, New Mexico, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05699226