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Study identifier: NCT05698576 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

TRANBERG® Transperineal MR/US Fusion Laser--Induced Thermal Therapy for Men With Prostate Cancer

Condition: Prostate Cancer · Adverse Effects Surgery · MRI  ·  Sponsor: Urological Research Network, LLC

PhaseNA
Planned participants20
Who can joinMale, 50 Years to 80 Years
Healthy volunteersYes

About this study

This study is set up as a phase I prospective, single center, device interventional pilot study carried in office setting under local anesthesia. It will assess the tolerance and safety of target fusion ablation of prostate cancer tumors using Laser Induced Thermal Therapy (TFA-LITT) guided by fusion imaging in men 50 to 80 years of age with low to intermediate risk prostate cancer Prostate Cancer is currently managed with in a discrete fashion where patients either enroll in active surveillance protocols (No intervention) or undergo full intervention via whole gland treatments - most commonly radical surgery or radiation. These treatments have not shown definitive gains in all cause survival and not uncommonly harbor undesirable adverse effects, most notably: impotency and incontinence. Such events elicit significant and noticeable changes on a male lifestyle and for most prostate cancer tumors are considered overtreatment. This study aims to evaluate the use of TFA-LITT in the office setting under local anesthesia - greatly decreasing patient perioperative surgical risk - focused on the organ sparing cancer lesion ablation, where organ function is preserved. The fundamental objective is to determine the tolerance and safety of TFA-LITT in men with low to intermediate risk prostate cancer, successful performed in the outpatient office-based setting under local anesthesia directed by fusion imaging. Secondary objectives include: 1-Biopsy proven cancer control of ablated are…

This description comes directly from the study's public registry record.

Talk to the study team

Cielo D Guerra, BS  ·  786-431-2014  ·  cielo@besturology.net

Luanda Perez, PA.C  ·  305-822-7227  ·  luanda@besturology.net

Always discuss trial participation with your own doctor first.

Locations (1)

Urology Specialist GroupHialeah, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05698576