Condition: Menstrual Cycle · Exercise · Women's Health · Sponsor: Karolinska Institutet
The menstrual cycle implies a basic difference in the biology of women and men but the effect of the hormonal variation on training protocols and physical performance is still not fully understood. Despite no existing evidence, the advice to periodize exercise according to the menstrual cycle has been widely spread among elite athletes, coaches, and sports federations. The advice is based on underpowered studies with considerable methodological weaknesses regarding determination of cycle phase, inclusion of athletes and lack of adequate control groups. The purpose of this randomized, controlled study is to evaluate the effect of exercise periodization on aerobic fitness during different phases of the menstrual cycle. Further, the effect will be related to premenstrual symptoms, body composition and skeletal muscle morphology, sex hormone receptors, metabolic enzymes, and markers of muscle protein synthesis. This study will be well controlled and follow methodology recommendations for menstrual cycle research in sports and exercise. Female athletes of fertile age will be randomized to different training regimens during three menstrual cycles (12 weeks): Group A: Training three times a week throughout the menstrual cycle. Group B: Follicular phase-based training five times a week during the follicular phase and thereafter once a week during the luteal phase. Group C: Luteal phase-based training five times a week during the luteal phase and once a week in the follicular phas…
This description comes directly from the study's public registry record.
Angelica L Hirschberg, Med dr · +46702559924 · angelica.hirschberg.linden@ki.se
Cecilia Fridén, Med dr · +46707415122 · cecilia.friden@ki.se
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| Angelica Lindén Hirschberg | Stockholm, Sweden | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05697263