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Study identifier: NCT05693909 Synced from ClinicalTrials.gov · July 28, 2026
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A Trial Testing SP-420 in Subjects With Transfusion-dependent β-thalassemia or Low-risk Myelodysplastic Syndromes

Condition: Beta Thalassemia Major Anemia · Myelodysplastic Syndrome  ·  Sponsor: Pharmacosmos A/S

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn about SP-420 ability to remove iron from organs in subjects with transfusion-dependent β-thalassemia or transfusion-dependent low-risk myelodysplastic syndrome. The main questions it aims to answer are: * How efficient is SP-420 in cleaning iron from the liver? * How is the safety and tolerability of ascending doses of SP-420? Participants will: * Take medication three times weekly * Attend up to 20 site visits * Undergo MRI scans

This description comes directly from the study's public registry record.

Talk to the study team

Pharmacosmos Clinical and non-clinical Department  ·  +45 5948 5959  ·  info@pharmacosmos.com

Always discuss trial participation with your own doctor first.

Locations (1)

Pharmacosmos Investigational SiteCopenhagen, DenmarkRecruiting

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Source record: clinicaltrials.gov/study/NCT05693909