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Study identifier: NCT05685238 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A

Condition: Haemophilia A · Haemophilia A With Inhibitors  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants451
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This study is looking at how Mim8 works in people with haemophilia A, who either have inhibitors or do not have inhibitors. Mim8 is a new medicine that will be used to avoid bleeding episodes. Mim8 works by replacing the function of the missing clotting factor VIII (FVIII). The study will last for up to 5.5 years. The duration of the study depends on when the participant enrolled in this study. The study will end if Mim8 is approved and marketed in participant's country during the study, or the study will end in June 2028, whichever comes first. Participants will get up to 262 injections; the number of injections depends on how often participants will get injections and how long time participants take part in the study. While taking part in this study, there are some restrictions about what medicine participants can use. The study doctor will tell the participants more about this. In case the participants experience bleeds, these can be treated with additional haemostatic medicine as agreed with the study doctor. Female participants cannot take part if they are pregnant, breast-feeding or plan to get pregnant during the study period.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (152)

Children's Hospital Los Angeles - EndocrinologyLos Angeles, California, United StatesRecruiting
UC Denver Hemoph & Thrombo CtrAurora, Colorado, United StatesRecruiting
Univ of Miami/SCCCMiami, Florida, United StatesRecruiting
St Joseph's Hospital FoundationTampa, Florida, United StatesActive Not Recruiting
Children's Healthcare AtlantaAtlanta, Georgia, United StatesRecruiting
Rush University Med. CntrChicago, Illinois, United StatesCompleted
Rush University Medical CenterChicago, Illinois, United StatesNot Yet Recruiting
Indiana Hemophilia-Thromb CtrIndianapolis, Indiana, United StatesCompleted
University of Iowa_Iowa CityIowa City, Iowa, United StatesRecruiting
Central Michigan UniversityDetroit, Michigan, United StatesRecruiting
Univ Hosp Cleveland Med CtrCleveland, Ohio, United StatesRecruiting
Dayton Children Hemostati CtrDayton, Ohio, United StatesRecruiting

+ 140 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05685238