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Study identifier: NCT05683223 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety

Condition: Social Anxiety Disorder  ·  Sponsor: Boston University Charles River Campus

PhaseNA
Planned participants240
Who can joinAll sexes, 18 Years to 50 Years
Healthy volunteersYes

About this study

The purpose of this clinical trial is to answer the question: can the investigators predict which adults with social anxiety disorder (SAD) will successfully respond to treatment? To answer this question, the investigators plan to recruit 190 adult participants who experience extreme forms of social anxiety to undergo brain imaging before and after 12 weeks of group cognitive behavioral therapy (CBT). Adults in the SAD group who do not respond enough to group CBT may be offered the opportunity to complete an additional 12 weeks of individual CBT while receiving SSRI medication (sertraline, see below) for SAD. Data collected from participants who experience anxiety will be compared to a group of 50 participants with little or no social anxiety, who will serve as a comparison group.

This description comes directly from the study's public registry record.

Talk to the study team

Anthony J Rosellini, PhD  ·  617-353-9610  ·  ajrosell@bu.edu

Amanda Desmarais, MA  ·  617-353-9610  ·  amanda99@bu.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Center for Anxiety and Related Disorders at Boston UniversityBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05683223