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Study identifier: NCT05682677 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Combined Neuromodulation and Cognitive Training for Post-mTBI Depression

Condition: Depression · Mild Traumatic Brain Injury · Concussion, Brain  ·  Sponsor: University of California, San Diego

PhaseNA
Planned participants72
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The primary goal of this clinical trial is to evaluate whether Personalized Augmented Cognitive Training (PACT) plus intermittent theta burst stimulation (iTBS) is effective for treating depression in Service Members, Veterans, and civilians who have sustained a mild TBI. Participants will receive PACT plus 20 sessions of iTBS or sham iTBS over 4 weeks. Assessments will occur at baseline, 2 weeks, 4 weeks, and 8 weeks. Researchers will compare the PACT+iTBS group to the PACT+sham iTBS group to see if PACT+iTBS is associated with more depression improvement.

This description comes directly from the study's public registry record.

Talk to the study team

Michelle Schy  ·  858-642-3848  ·  mschy@health.ucsd.edu

Janae Wyckoff  ·  858-642-3848  ·  jwyckoff@health.ucsd.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCSDLa Jolla, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05682677