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Study identifier: NCT05681780 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

Condition: Non Small Cell Lung Cancer · Stage IV Non-small Cell Lung Cancer · Recurrent Non Small Cell Lung Cancer  ·  Sponsor: H. Lee Moffitt Cancer Center and Research Institute

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To determine the effect of a special preparation of cells, called tumor-infiltrating lymphocytes (TIL) stimulated with CD40L, when given with the drug nivolumab, for patients with EGFR, ALK, ROS1, or HER2-genomically altered lung cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Ben Creelan  ·  813-745-4541  ·  Ben.Creelan@moffitt.org

Always discuss trial participation with your own doctor first.

Locations (1)

Moffitt Cancer CenterTampa, Florida, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05681780