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Study identifier: NCT05681468 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources

Condition: PreDiabetes · Diabetes Mellitus, Type 2 · Overweight and Obesity  ·  Sponsor: University of Alberta

PhaseNA
Planned participants175
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare a healthy KETO diet supplemented with canola oil (KETO-Can) compared to a traditional KETO diet high in saturated fat (KETO-Sat) and low-fat diet (LFD) in adults at high risk of or diagnosed with type 2 diabetes. The main question\[s\] it aims to answer are: * Effects on CVD risk factors (plasma cholesterol, TG, ApoB100, glucose, insulin and HbA1C). * Effects on systemic inflammation and immune function. * Adherence to interventions. Participants will be randomized into 1 of the dietary treatments during which they will follow a Keto or a low-fat diet. Comparisons among groups at 3 and 6 months of intervention will be conducted.

This description comes directly from the study's public registry record.

Talk to the study team

Paulina Blanco Cervantes, MSc  ·  7804929506  ·  blancoce@ualberta.ca

Always discuss trial participation with your own doctor first.

Locations (1)

University of AlbertaEdmonton, Alberta, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05681468