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Study identifier: NCT05674994 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Glucocorticoids Versus Placebo for the Treatment of Acute Exacerbation of Idiopathic Pulmonary Fibrosis

Condition: Acute Exacerbation of Idiopathic Pulmonary Fibrosis  ·  Sponsor: Fondation Hôpital Saint-Joseph

PhasePhase 3
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is associated with a poor prognosis, with a 3-month mortality rate of over 50%. To date, no treatment has been proven to be effective in AI-FPI. The interest of glucocorticoids is controversial and needs to be confirmed. This confirmation is mandatory to validate the improvement of the prognosis of EA-IPF under this treatment but also to search for unsuspected deleterious effects as it has been shown with immunosuppressants in stable idiopathic pulmonary fibrosis.

This description comes directly from the study's public registry record.

Talk to the study team

Jean-Marc NACCACHE, MD  ·  144126747  ·  jmnaccache@ghpsj.fr

Helene BEAUSSIER, PharmD, PhD  ·  144127883  ·  crc@ghpsj.fr

Always discuss trial participation with your own doctor first.

Locations (29)

CHU ANgersAngers, FranceRecruiting
CHU de BesanconBesançon, FranceRecruiting
Hôpital AvicenneBobigny, FranceNot Yet Recruiting
CHU BOrdeauxBordeaux, FranceRecruiting
CHU CaenCaen, FranceRecruiting
CHU Clermont-FerrandClermont-Ferrand, FranceNot Yet Recruiting
CHICCréteil, FranceRecruiting
CHU de DijonDijon, FranceRecruiting
CHU GrenobleGrenoble, FranceNot Yet Recruiting
CHRU LilleLille, FranceNot Yet Recruiting
Hospices Civils de LyonLyon, FranceRecruiting
Hôpital NordMarseille, FranceRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05674994