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Study identifier: NCT05672836 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ENAVOgliflozin Outcome Trial in Patients With Severe Aortic Stenosis After Transcatheter Aortic Valve Replacement

Condition: Aortic Valve Stenosis · Heart Failure  ·  Sponsor: Duk-Woo Park, MD

PhasePhase 4
Planned participants1040
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this trial is to to determine whether use of a novel SGLT2 inhibitor, Enavogliflozin 0.3 mg once daily is superior to placebo, when added to standard-of-care, in reducing the composite of major cardiovascular events and Heart Failure events (hospitalization for Heart Failure or urgent Heart Failure visit) among patients who underwent transcatheter aortic valve replacement for severe aortic stenosis and with heart failure with preserved ejection fraction.

This description comes directly from the study's public registry record.

Talk to the study team

Jeong-youn Bae, Project manager  ·  82230107259  ·  cvcrc10@amc.seoul.kr

Always discuss trial participation with your own doctor first.

Locations (31)

Bucheon Sejong HospitalBucheon-si, South KoreaRecruiting
Gyeongsang National University Changwon HospitalChangwon, South KoreaRecruiting
Daegu Catholic University Medical CenterDaegu, South KoreaRecruiting
Keimyung University Dongsan Medical CenterDaegu, South KoreaRecruiting
Kyungpook National University HospitalDaegu, South KoreaRecruiting
Yeungnam University Medical CenterDaegu, South KoreaWithdrawn
Chungnam National University HospitalDaejeon, South KoreaRecruiting
The Catholic University of Korea, Daejeon ST. Mary's HospitalDaejeon, South KoreaRecruiting
Gangneung Asan HospitalGangneung, South KoreaRecruiting
Chonnam National University HospitalGwangju, South KoreaRecruiting
Inje University Ilsan Paik HospitalIlsan, South KoreaRecruiting
Gachon University Gil HospitalIncheon, South KoreaRecruiting

+ 19 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05672836