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Study identifier: NCT05672121 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Tolerability of KH631 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

Condition: Age-Related Macular Degeneration  ·  Sponsor: Chengdu Origen Biotechnology Co., Ltd.

PhasePhase 1/Phase 2
Planned participants42
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

KH631 is a adeno-associated virus (AAV) vector-based gene therapy for subretinal injection. The long-term, stable therapeutic protein after one time injection for nAMD could potentially reduce the treatment burden and maintain vision.

This description comes directly from the study's public registry record.

Talk to the study team

Qiang Zheng  ·  86 13880331037  ·  zhengqiang@cnkh.com

Shanshan Ji  ·  86 18188058101  ·  022078@cnkh.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Tongren Hospital, Capital Medical UniversityBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05672121