Condition: Invasive Mechanical Ventilation · Sponsor: Technische Universität Dresden
Invasive mechanical ventilation is one of the most important and life-saving therapies in the intensive care unit (ICU). In most severe cases, extracorporeal lung support is initiated when mechanical ventilation is insufficient. However, mechanical ventilation is recognised as potentially harmful, because inappropriate mechanical ventilation settings in ICU patients are associated with organ damage, contributing to disease burden. Studies revealed that mechanical ventilation is often not provided adequately despite clear evidence and guidelines. Variables at the ventilator and extracorporeal lung support device can be set automatically using optimization functions and clinical recommendations, but the handling of experts may still deviate from those settings depending upon the clinical characteristics of individual patients. Artificial intelligence can be used to learn from those deviations as well as the patient's condition in an attempt to improve the combination of settings and accomplish lung support with reduced risk of damage.
This description comes directly from the study's public registry record.
Jakob Wittenstein, MD · +49 351 458 19887 · jakob.wittenstein@ukdd.de
Thea Koch, PhD · thea.koch@ukdd.de
Always discuss trial participation with your own doctor first.
| Cleveland Clinic Foundation, Cleveland, USA | Cleveland, Ohio, United States | Recruiting |
| University Hospital Carl Gustav Carus Dresden | Dresden, Germany | Recruiting |
| Institut Fur Angewandte Informatik (Infai) Ev | Leipzig, Germany | Active Not Recruiting |
| Institut Mihajlo Pupin | Belgrade, Serbia | Active Not Recruiting |
| Better Care Sl | Sabadell, Spain | Active Not Recruiting |
| Fundacio Parc Tauli | Sabadell, Spain | Completed |
| Fundacion Publica Andaluza Progreso Y Salud | Seville, Spain | Active Not Recruiting |
| Inselspital, Universitätsspital Bern | Bern, Switzerland | Completed |
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Source record: clinicaltrials.gov/study/NCT05668637