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Study identifier: NCT05667454 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

MAD Trial: Myopia Atropine Dose

Condition: Progressive Myopia  ·  Sponsor: Erasmus Medical Center

PhasePhase 3
Planned participants550
Who can joinAll sexes, 6 Years to 11 Years
Healthy volunteersNo

About this study

The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety, adherence, and reasons for nonresponse. Subjects will use Atropine eye drops for a period of 3 years, followed by a 2 year observational period.

This description comes directly from the study's public registry record.

Talk to the study team

Jan Roelof Polling, Dr.  ·  +31628449254  ·  j.polling@erasmusmc.nl

Trialbureau Oogheelkunde  ·  +31107039740  ·  research.oogheelkunde@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (20)

FlevoziekenhuisAlmere Stad, NetherlandsRecruiting
OLVG, locatie OostAmsterdam, NetherlandsRecruiting
Ophthalmologistenpraktijk DelflandDelft, NetherlandsRecruiting
Reinier de Graaf GasthuisDelft, NetherlandsRecruiting
Deventer ZiekenhuisDeventer, NetherlandsRecruiting
Albert Schweitzer ziekenhuisDordrecht, NetherlandsRecruiting
Bergman Clinics - EdeEde, NetherlandsRecruiting
Admiraal de Ruyter ZiekenhuisGoes, NetherlandsRecruiting
Frisius MCHeerenveen, NetherlandsRecruiting
Oogcentrum NoordhollandHeerhugowaard, NetherlandsRecruiting
Leiden University Medical CenterLeiden, NetherlandsRecruiting
Bergman Clinics - LelystadLelystad, NetherlandsRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05667454