● Recruiting

A Study to Determine the Efficacy and Safety of Luspatercept in Adult Participants and to Evaluate the Safety and Pharmacokinetics in and Adolescent Participants With Alpha (α)-Thalassemia

Condition: Anemia · Sponsor: Bristol-Myers Squibb

PhasePhase 2

Planned participants189

Who can joinAll sexes, 12 Years to no upper limit

Healthy volunteersNo

About this study

The purpose of the study is to evaluate the efficacy and safety of luspatercept plus best supportive care (BSC) vs placebo plus BSC on anemia in adult participants with α-thalassemia hemoglobin H (HbH) disease and determine the safety and drug levels in adolescent participants.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com · 855-907-3286 · Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (36)

Local Institution - 0008	Halifax, Nova Scotia, Canada	Withdrawn
Sun Yat-sen Memorial Hospital, Sun Yat-Sen University	Guangzhou, GD, China	Recruiting
Nanfang Hospital of Southern Medical University	Guangzhou, GD, China	Recruiting
The First People's Hospital of Foshan	Foshan, Guangdong, China	Recruiting
Maoming People's Hospital	Maoming Shi, Guangdong, China	Recruiting
Shenzhen Second People's Hospital	Shenzhen Shi, Guangdong, China	Recruiting
Liuzhou People's Hospital	Liuzhou, Guangxi, China	Recruiting
People's Liberation Army The 923rd Hospital	Nanning, GX, China	Recruiting
Local Institution - 0011	Haikou, Hainan, China	Active Not Recruiting
Local Institution - 0012	Kunming, Yunnan, China	Completed
Hainan General Hospital	Haikou, China	Recruiting
The First Affiliated Hospital of Guangxi Medical University	Nanning, China	Recruiting

+ 24 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05664737