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Study identifier: NCT05664412 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

Condition: 22Q11 Deletion Syndrome · tACS  ·  Sponsor: Stephan Eliez

PhaseNA
Planned participants40
Who can joinAll sexes, 14 Years to 25 Years
Healthy volunteersNo

About this study

The purpose of this project is to explore the effects of transcranial alternating current stimulation (tACS) in children, adolescents and young adults with a 22q11.2 microdeletion. The main aim of the present research project is to investigate the effects of repeated, individually tuned high-density (HD) tACS on cognition (i.e., WM performance) and related neuroimaging markers in carriers of the 22q11DS. As cognitive deficits, most notably WM impairment, are among the earliest signs of psychotic disorders, interventions during adolescence aimed at reducing cognitive decline in at-risk individuals may prove effective in delaying or even preventing the later emergence of psychotic symptoms.

This description comes directly from the study's public registry record.

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Locations (1)

University of GenevaGeneva, Canton of Geneva, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT05664412