Condition: Specific Antibody Deficiency · Predominantly Antibody Deficiencies · Sponsor: University Hospital, Lille
The DETECT study aims to demonstrate the importance of detecting SPAD in adult patients with recurrent benign and/or severe unexplained bacterial upper/lower respiratory tract infections. Unlike children in whom the deficit may be transient, long-term strategies are warranted in SPAD adult patients to prevent severe infections and lung disability. Beyond the diagnosis of this still unrecognized PID in adult patients, the investigators want to assess the impact of prophylactic antibiotics or IgRT on infections prevention and on quality of life in adult patients with the most severe clinical phenotypes, recurrent infections with high frequency of antibiotics take and/or recurrent infections with complications like bronchiectasis and/or severe infections requiring hospitalizations.
This description comes directly from the study's public registry record.
Guillaume LEFEVRE, MD,PhD · 0320445962 · guillaume.lefevre@chu-lille.fr
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| Lille University Hospital | Lille, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05664035