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Study identifier: NCT05663489 Synced from ClinicalTrials.gov · July 29, 2026
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Neurobiological Markers of Treatment Response for Anxiety and OCD

Condition: Obsessive-Compulsive Disorder · Social Anxiety Disorder · Panic Disorder  ·  Sponsor: Haukeland University Hospital

PhaseN/A
Planned participants500
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersYes

About this study

Obsessive-compulsive disorder (OCD) and anxiety disorders are common and debilitating conditions which are often chronic when treatment is not provided. International guidelines recommend cognitive behavioral therapy (CBT) as the first-line treatment, and research has shown that CBT can be delivered over a concentrated period of time. The Bergen 4-Day Treatment (B4DT) is an exposure-based treatment which is delivered over four consecutive days. B4DT has been shown to induce rapid and long-lasting remission in around 70% of patients. This provides a platform for studying psychological and neurobiological changes associated with treatment response and non-response. The present study will investigate longitudinal changes in psychological measures and DNA methylation in patients who receive the B4DT, as well as a subset will also undergo multimodal brain imaging.

This description comes directly from the study's public registry record.

Talk to the study team

Bjarne Hansen, PhD  ·  +4792090765  ·  bjarne.kristian.aaslie.hansen@helse-bergen.no

Always discuss trial participation with your own doctor first.

Locations (1)

Bergen Center for Brain PlasticityBergen, Vestland, NorwayRecruiting

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Source record: clinicaltrials.gov/study/NCT05663489