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Study identifier: NCT05659797 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

FES BPET-DBT in Newly Diagnosed Breast Cancer

Condition: Breast Cancer  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhaseEARLY_Phase 1
Planned participants20
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Patients with newly diagnosed primary estrogen-receptor (ER) positive breast cancer, with at least one breast lesion that is 1.0 cm in diameter or greater, may be eligible for this study. Patients may participate in this study if they are at least 18 years of age. Up to 20 evaluable subjects will participate in a single imaging cohort. Study subjects will undergo imaging of the breast with a novel device combining dedicated Breast Positron Emission Tomography (BPET) and Digital Breast Tomosynthesis (DBT) following intravenous injection of \[18F\]-Fluoroestradiol (FES). This is an observational study; FES-BPET/DBT will not be used to direct treatment decisions. While patients and referring physicians will not be blinded to the FES-BPET/DBT results, treatment decisions are made by the treating physicians based upon standard clinical imaging.

This description comes directly from the study's public registry record.

Talk to the study team

Erin o Schubert  ·  2155736569  ·  erin.schubert@pennmedicine.upenn.edu

Hannah Straughn  ·  hannah.straughn@pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05659797