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Study identifier: NCT05655403 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of Step Training in Older Adults with Mild Dementia

Condition: Dementia  ·  Sponsor: The Hong Kong Polytechnic University

PhaseNA
Planned participants145
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Step training has been shown to be effective at reducing the incidence of falls and improving related risk factors, including choice stepping, in healthy older adults. However, the effects of step training have not been investigated in OWMD. The primary objective of the proposed project will be to assess the effects of a step-training program involving concurrent stepping and visuospatial tasks on choice stepping, prefrontal cortex functioning during choice stepping, and fall-related outcomes (i.e., step length, lower-limb muscle strength, balance, mobility, dual-task ability, and fear of falling) in OWMD. The prefrontal cortex is responsible for the executive functions such as attention and inhibitory function, which are integral to choice stepping reaction time tasks. However, the effects of step training on prefrontal cortex functioning during choice stepping in OWMD remain unclear. The neural mechanisms underlying the potential effects of step training on choice stepping have never been investigated in this population. Therefore, the secondary objective of the proposed project will be to evaluate the mediating effects of changes in the prefrontal cortex functioning during choice stepping on the potential benefits of a step-training program for choice stepping in OWMD. The proposed project will provide robust evidence to support the use of step training to improve choice stepping and reduce the risk of falls in OWMD. Disentangling the neural mechanisms underlying the eff…

This description comes directly from the study's public registry record.

Talk to the study team

Wayne LS Chan, PhD  ·  +852 27666742  ·  wayne.ls.chan@polyu.edu.hk

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Locations (1)

The Hong Kong Polytechnic UniversityHong Kong, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT05655403