Condition: Pre-Bronchiolitis Obliterans Syndrome · Sponsor: Renovion, Inc.
The goal of this Phase 3 clinical trial is to compare ARINA-1 (a nebulized immunomodulatory agent) plus Standard of Care vs Standard of Care alone. The main question it aims to answer are: * Evaluate the effectiveness of ARINA-1 in preventing bronchiolitis obliterans syndrome (BOS) progression in participants with a bilateral lung transplant * To evaluate the effectiveness of ARINA-1 on improving quality of life decline and preventing or delaying the use of augmented immunosuppression in participants with pre-BOS relative to SOC. Participants will have clinic visits at screening, randomization (day 1) and weeks 4, 12, 18, and 24. After week 24, participants will have clinic visits at weeks 32, 40, and 48. Participants will also have a telehealth visit on day 2 and phone calls to assess adverse events (AEs), serious adverse events (SAEs), and review patient education will occur during weeks 5, 8, 36, and 44.
This description comes directly from the study's public registry record.
Carolyn Durham, PhD · 919-240-7034 · info@renovion.com
Will Anderson · 919-240-7034 · info@renovion.com
Always discuss trial participation with your own doctor first.
| Dignity Health - St. Joseph's Hospital and Medical Center | Phoenix, Arizona, United States | Withdrawn |
| University of California Los Angeles School of Medicine | Los Angeles, California, United States | Recruiting |
| University of California San Diego Health | San Diego, California, United States | Recruiting |
| Advent Health | Orlando, Florida, United States | Recruiting |
| University of South Florida | Tampa, Florida, United States | Recruiting |
| Loyola University Medical Center | Maywood, Illinois, United States | Recruiting |
| University of Iowa Hospital | Iowa City, Iowa, United States | Recruiting |
| Johns Hopkins Hospital | Baltimore, Maryland, United States | Recruiting |
| University of Minnesota Medical School | Minneapolis, Minnesota, United States | Withdrawn |
| Washington University School of Medicine | St Louis, Missouri, United States | Recruiting |
| Columbia University Irving Medical Center | New York, New York, United States | Recruiting |
| Cleveland Clinic | Cleveland, Ohio, United States | Recruiting |
+ 8 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05654922