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Study identifier: NCT05654454 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Safety and Efficacy Study of Bevacizumab, Paclitaxel, Carboplatin Compared to Avastin® in Non-Small Cell Lung Cancer

Condition: Non-Small Cell Lung Cancer  ·  Sponsor: Mabscale, LLC

PhasePhase 3
Planned participants620
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

BEV-III/2022 is a double-blind randomized multicenter clinical trial comparing efficacy of bevacizumab (manufactured by Mabscale, LLC) and paclitaxel plus carboplatin to Avastin® and paclitaxel plus carboplatin in first-line treatment for patients with advanced (unresectable, locally advanced, recurrent or metastatic) non-squamous NSCLC. The purpose of the study is to demonstrate equivalence of efficacy and safety of bevacizumab (manufactured by Mabscale, LLC) to Avastin®. Study includes pharmacokinetics assessment.

This description comes directly from the study's public registry record.

Talk to the study team

Alexander Generalov, MD  ·  +74997149289  ·  generalov.a@benerix.ru

Always discuss trial participation with your own doctor first.

Locations (28)

Arkhangelsk Clinical Oncological DispensaryArkhangelsk, RussiaRecruiting
State Budget Healthcare Institution Ivanovo Regional Oncology DispensaryIvanovo, RussiaRecruiting
Kaluga Regional Clinical Oncology DispensaryKaluga, RussiaRecruiting
Regional clinical oncological dispensary n.a.SigalKazan', RussiaRecruiting
Burdenko Main Military Clinical HospitalMoscow, RussiaRecruiting
Hadassah Medical MoscowMoscow, RussiaWithdrawn
National Medical Oncology Research Center n.a. N.N. BlokhinaMoscow, RussiaNot Yet Recruiting
Murmansk Regional Clinical HospitalMurmansk, RussiaRecruiting
Nizhny Novgorod Regional Oncology DispensaryNizhny Novgorod, RussiaRecruiting
Novosibirsk oncologic dispensaryNovosibirsk, RussiaRecruiting
Omsk clinical oncologic dispensaryOmsk, RussiaRecruiting
Perm Edge Clinical HospitalPerm, RussiaNot Yet Recruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05654454