Condition: Obesity · Healthy Lifestyle · Sponsor: Cedars-Sinai Medical Center
All participants will undergo baseline biopsies of subcutaneous abdominal adipose tissue for cellular/molecular profiling via snRNA-seq and metabolic/physiological assessments (insulin sensitivity, glucose tolerance, and β-cell function). Older obese participants will be randomized into three arms: lifestyle intervention (n=24), senolytics (n=24), or placebo (n=24).
This description comes directly from the study's public registry record.
Nicolas Musi, MD · 210-562-6140 · nicolas.musi@cshs.org
Arianne Aslamy, MD · 424-315-0685 · Arianne.Aslamy@cshs.org
Always discuss trial participation with your own doctor first.
| Cedars Sinai Medical Center | Los Angeles, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05653258