● Recruiting

Prophylaxis With Direct-acting Antivirals for Kidney Transplantation From HCV-Infected Donors to Uninfected Recipients

Condition: HCV · Sponsor: Johns Hopkins University

PhaseNA

Planned participants120

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This study is being done to find out the best time to start medication for Hepatitis C Virus (HCV) in HCV-negative recipients of HCV-positive (HCV D+/R-) kidney transplants. Participants will be randomized into one of two groups: Arm 1 - Prophylaxis: This group will start the HCV medication before transplant and will take a shorter course of HCV medication for 2 weeks. Arm 2 - Transmit and Treat: This group will start the HCV medication after transplant and will take the full course (12 weeks) of HCV medication.

This description comes directly from the study's public registry record.

Talk to the study team

Christine Durand, MD · 410-955-5684 · cdurand2@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (9)

University of California San Diego	La Jolla, California, United States	Recruiting
Loma Linda University Health	Loma Linda, California, United States	Recruiting
Johns Hopkins University	Baltimore, Maryland, United States	Recruiting
NYU Langone Health	New York, New York, United States	Recruiting
Icahn School of Medicine at Mount Sinai	New York, New York, United States	Recruiting
University of Pittsburgh Medical Center	Pittsburgh, Pennsylvania, United States	Recruiting
University of Utah Medical Center	Salt Lake City, Utah, United States	Recruiting
Virginia Commonwealth University	Richmond, Virginia, United States	Recruiting
University of Wisconsin, Madison	Madison, Wisconsin, United States	Terminated

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Source record: clinicaltrials.gov/study/NCT05653232