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Study identifier: NCT05652335 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

Condition: Relapsed or Refractory Multiple Myeloma · Previously Treated Amyloid Light-chain (AL) Amyloidosis  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 1
Planned participants180
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of this study is to identify the recommended phase 2 dose (RP2D\[s\]) and schedule(s) to be safe for JNJ-79635322 in Part 1 (dose escalation), and to characterize the safety and tolerability of JNJ-79635322 at the RP2D(s) selected and in disease subgroups in Part 2 (dose expansion).

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (29)

City of HopeDuarte, California, United StatesRecruiting
City of Hope Orange County Lennar Foundation Cancer CenterIrvine, California, United StatesRecruiting
University of California San FranciscoSan Francisco, California, United StatesRecruiting
Colorado Blood Cancer InstituteDenver, Colorado, United StatesRecruiting
Icahn School of Medicine at Mt. SinaiNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Levine Cancer InstituteCharlotte, North Carolina, United StatesRecruiting
University of Pennsylvania Division of Hematology Oncology Perelman Center for Advanced MedicinePhiladelphia, Pennsylvania, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
UZ AntwerpenEdegem, BelgiumRecruiting
UZ GentGhent, BelgiumRecruiting
CHU de LiegeLiège, BelgiumRecruiting

+ 17 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05652335