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Study identifier: NCT05648175 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Comparing Clinical Decision-making of AI Technology to a Multi-professional Care Team in ECBT for Depression

Condition: Depression  ·  Sponsor: Dr. Nazanin Alavi

PhaseNA
Planned participants186
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Depression is a leading cause of disability worldwide, affecting up to 300 million people globally. Despite its high prevalence and debilitating effects, only one-third of patients newly diagnosed with depression initiate treatment. Electronic cognitive behavioural therapy (e-CBT) is an effective treatment for depression and is a feasible solution to make mental health care more accessible. Due to its online format, e-CBT can be combined with variable therapist engagement to address different care needs. Typically, a multi-professional care team determines which combination therapy is the most beneficial to the patient. However, this process can add to the costs of these programs. Artificial intelligence (AI) technology has been proposed to offset these costs. Therefore, this study aims to determine a cost-effective method to decrease depressive symptoms and increase treatment adherence to e-CBT. This will be done by comparing AI technology to a multi-professional care team when allocating the correct intensity of care for individuals diagnosed with depression. This study is a double-blinded randomized controlled trial recruiting individuals (n = 186) experiencing depression according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). The degree of care intensity a participant will receive will be randomly decided by either: (1) a machine learning algorithm (n = 93), or (2) an assessment made by a group of healthcare professionals (n = 93). Sub…

This description comes directly from the study's public registry record.

Talk to the study team

Nazanin Alavi, MD FRCPC  ·  613-544-3310  ·  nazanin.alavitabari@kingstonhsc.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Hotel Dieu HospitalKingston, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05648175