● Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Condition: Aortic Stenosis · Sponsor: Novartis Pharmaceuticals

PhasePhase 2

Planned participants502

Who can joinAll sexes, 50 Years to 80 Years

Healthy volunteersNo

About this study

The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in slowing the progression of calcific aortic valve stenosis.

This description comes directly from the study's public registry record.

Talk to the study team

Novartis Pharmaceuticals · 1-888-669-6682 · novartis.email@novartis.com

Novartis Pharmaceuticals · +41613241111

Always discuss trial participation with your own doctor first.

Locations (140)

Heart Center Research Llc	Huntsville, Alabama, United States	Recruiting
Cardiovascular Res Found	Beverly Hills, California, United States	Recruiting
National Heart Institute	Beverly Hills, California, United States	Recruiting
Flourish Clinical Resrch Covin	Covina, California, United States	Recruiting
Valley Clinical Trials	Northridge, California, United States	Recruiting
Stanford University Medical Center	Palo Alto, California, United States	Recruiting
University Of California San Diego	San Diego, California, United States	Recruiting
UC San Francisco Medical Center	San Francisco, California, United States	Recruiting
Excel Medical Clinical Trials LLC	Boca Raton, Florida, United States	Withdrawn
Nova Clinical Research LLC	Bradenton, Florida, United States	Recruiting
Flourish Res Acq LLC North Miami	Miami, Florida, United States	Recruiting
Inpatient Research Clinical LLC	Miami Lakes, Florida, United States	Recruiting

+ 128 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05646381