Condition: Stroke, Ischemic · Transient Ischemic Attack · Coagulation Disorder · Sponsor: Cwm Taf University Health Board (NHS)
Annually 100,000 strokes occur, placing stroke as the largest cause of disability in the UK. 90% of strokes are preventable, leading to national focus on programmes including "The National Stroke Programme" to act on preventing, treating, and improving post-stroke care. Importantly, over 25% of ischaemic stroke sufferers have previously had a Transient Ischaemic Attack (TIA), which presents the biggest concern for TIA patients. There are no measures which reliably identify TIA patients most likely to suffer a stroke. Novel biomarkers for predicting stroke are key to addressing this problem. The PREDICT-EV study aims to screen 300 TIA patients and follow them over 12-months. The investigators will determine if a novel biomarker we've identified to increase thrombotic risk (endothelial derived extracellular vesicles) and the resulting increased prothrombin time is associated with patients at highest risk of stroke.
This description comes directly from the study's public registry record.
Jessica Williams, PhD · 02920417077 · jwilliams3@cardiffmet.ac.uk
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| Prince Charles Hospital | Merthyr Tydfil, United Kingdom | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05645081