Condition: Poliomyelitis · Sponsor: PATH
The purpose of this clinical trial is to assess the safety and tolerability (primary objective), immunogenicity (primary and secondary objectives), fecal shedding of vaccine viruses (secondary objective) and the potential for neurovirulence of shed virus (secondary objective) of a novel oral polio type 1 vaccine, nOPV1, as compared to Sabin monovalent type 1 vaccine controls (mOPV1), in healthy young children (192 subjects), infants (720 subjects), and neonates (1320 subjects).
This description comes directly from the study's public registry record.
Tushar Tewari, MD · +91 11 4064 0005 · ttewari@path.org
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| International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) | Dhaka, Bangladesh | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05644184