Condition: Respiratory Insufficiency · Diaphragm Injury · Lung Injury · Sponsor: University Health Network, Toronto
Mechanical ventilation can lead to diaphragm and lung injury. During mechanical ventilation, the diaphragm could be completely rested or it could be overworked, either of which may cause diaphragm injury. Mechanical stress and strain applied by mechanical ventilation or by the patient's own respiratory muscles can also cause injury to the lungs. Diaphragm and lung injury are associated with increased morbidity and mortality. Throughflow is a novel system that can reduce dead space without the need to increase the tidal ventilation, reducing the ventilatory demands and respiratory drive.
This description comes directly from the study's public registry record.
Rongyu ( Cindy) Jin · 4163404800 · rongyu.jin@uhn.ca
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| University Health Network | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05642832