← Eichor
Study identifier: NCT05642455 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

SPEARHEAD-3 Pediatric Study

Condition: Synovial Sarcoma · Malignant Peripheral Nerve Sheath Tumor (MPNST) · Neuroblastoma (NBL)  ·  Sponsor: USWM CT, LLC

PhasePhase 1/Phase 2
Planned participants20
Who can joinAll sexes, 2 Years to 21 Years
Healthy volunteersNo

About this study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (10)

Stanford UniversityPalo Alto, California, United StatesRecruiting
National Institutes of HealthBethesda, Maryland, United StatesRecruiting
Dana Farber Cancer InstituteBoston, Massachusetts, United StatesNot Yet Recruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting
Memorial Sloan Kettering KidsNew York, New York, United StatesNot Yet Recruiting
Duke University School of MedicineDurham, North Carolina, United StatesNot Yet Recruiting
Cincinnati Children's Hospital Medical CenterCincinnati, Ohio, United StatesRecruiting
Children's Hospital of PhiledephiaPhiladelphia, Pennsylvania, United StatesRecruiting
Seattle Children's HospitalSeattle, Washington, United StatesNot Yet Recruiting
University of Wisconsin Cancer CenterMadison, Wisconsin, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05642455