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Study identifier: NCT05641688 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

[18F]PI-2620 Phase 3 Histopathological Study

Condition: Alzheimer Disease  ·  Sponsor: Lantheus Biosciences Ltd.

PhasePhase 3
Planned participants200
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This study is an open-label, multi-center, non-randomized pivotal Phase 3 study to assess the efficacy and safety of PET imaging with \[18F\]PI-2620 for detection of tau deposition in subjects with Alzheimer's disease (AD) and controls during lifetime when compared to histopathology obtained after death and completion of brain autopsy.

This description comes directly from the study's public registry record.

Talk to the study team

Audrey Perrotin, PhD  ·  +49 (0)30 461 1246 03  ·  clinicaltrials@life-mi.com

Aleksandar Jovalekic, PhD  ·  +49 (0)30 461 1246 03  ·  clinicaltrials@life-mi.com

Always discuss trial participation with your own doctor first.

Locations (25)

Barrow Neurological InstitutePhoenix, Arizona, United StatesRecruiting
Banner Sun Health Research InstituteSun City, Arizona, United StatesRecruiting
UC Los AngelesLos Angeles, California, United StatesRecruiting
Esperanza ClinicalMurrieta, California, United StatesRecruiting
Sutter HealthSan Francisco, California, United StatesRecruiting
Galiz ResearchHialeah, Florida, United StatesRecruiting
UF College of Medicine - JacksonvilleJacksonville, Florida, United StatesWithdrawn
K2 Medical ResearchLady Lake, Florida, United StatesRecruiting
K2 Medical ResearchMaitland, Florida, United StatesRecruiting
ClinCloud ResearchMelbourne, Florida, United StatesRecruiting
Miami Jewish Health SystemsMiami, Florida, United StatesRecruiting
The Roskamp InstituteSarasota, Florida, United StatesTerminated

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05641688