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Study identifier: NCT05641428 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparison of Point-of-care Produced CAR T-cell with Commercial CAR T-cells in Patients with R/R LBCL

Condition: NHL · DLBCL - Diffuse Large B Cell Lymphoma  ·  Sponsor: University Medical Center Groningen

PhasePhase 2
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A phase II, multi-center study to compare the feasibility, and clinical efficacy of local manufacturing of CD19-directed CAR T-cells (ARI-0001 CAR T-cells) with commercial produced CAR T-cells (for example axicabtagene ciloleucel, a CD19 targeting commercially available CAR T-cell) in patients with relapsed or refractory (R/R) DLBCL.

This description comes directly from the study's public registry record.

Talk to the study team

T. (Tom) van Meerten  ·  +31 (0)10 7041560  ·  hdc@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (7)

NL-Amsterdam-AMCAmsterdam, NetherlandsRecruiting
NL-Groningen-UMCGGroningen, NetherlandsRecruiting
NL-Leiden-LUMCLeiden, NetherlandsRecruiting
NL-Maastricht-MUMCMaastricht, NetherlandsRecruiting
NL-Nijmegen-RADBOUDUMCNijmegen, NetherlandsRecruiting
NL-Rotterdam-ERASMUSMCRotterdam, NetherlandsRecruiting
NL-Utrecht-UMCUTRECHTUtrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05641428